Error while sending mail from SAP system

Hi all,

I configured SAP connect  in ecc6.0 ehp7 while sending mail using tx sost i am error

Message cannot be transferred to node SMTP due to connection error (final) , below is the icm log.

ERROR => IcmPlAllocBuf: MpiGetOutbuf failed (rc = 14(MPI_ESTALE: outdated MPI handle)) [icxxplugin.c 1222]

ERROR => SMTP SmtpClientClose: alloc failed, rc = -3 [smtp_plg.c   3738]

ERROR => IcmBufFree(id=0/32): MpiFreeBuf failed (rc=14), MPI_ESTALE: outdated MPI handle [icxxplugin.c 165

ERROR => IcmConnClose: PlugInStopConn failed (rc=701) [icxxconn.c   3433]

can any one please help on this

Thanks,

Narendar.